Evolution of the Human Genome I by Naruya Saitou

Author:Naruya Saitou
Language: eng
Format: epub
Publisher: Springer Japan, Tokyo

Population

African

European

Asian

African

47.0

European

41.1

30.4

Asian

40.0

26.8

32.3

From Takezaki and Nei (2009)

Table 7.2 shows the MADs of OR genes. The average MADs among populations are higher for functional genes than for pseudogenes among human populations (4.7 and 2.4) as well as between human and chimpanzee (16 and 11). This suggests that CNV of functional OR genes is under positive selection . Thus, the pattern of CNV in OR genes is complex, and it may not necessarily evolve neutrally, as mentioned earlier.Table 7.2MAD of copy number of OR genes

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